![]() Surg Oncol Clin N Am 5(1):33–41 ReviewĪlex JC, Sasaki CT, Krag DN, Wenig B, Pyle PB (2000) Sentinel lymph node radiolocalization in head and neck squamous cell carcinoma. Surg Oncol 2:137–143Īlex JC, Krag DN (1996) The gamma-probe-guided resection of radiolabeled primary lymph nodes. This process is experimental and the keywords may be updated as the learning algorithm improves.Īlex JC, Krag DN (1993) Gamma probe guided lymph node localization in malignant melanoma. ![]() These keywords were added by machine and not by the authors. This chapter describes the technique, its accuracy and current applications, and its potential role in the management of patients with early oral/oropharyngeal squamous cell cancer. The sentinel node biopsy procedure provides a means of obtaining tissue for pathological staging of the cervical lymph node basin, while potentially avoiding the morbidity of an elective neck dissection. However, only one-fourth of cT1-T2 patients are found to harbor occult nodal disease, and the remainder of patients may be unnecessarily exposed to the considerable morbidity associated with neck dissection. The gold standard for staging the cervical nodes is elective neck dissection, providing both diagnostic and therapeutic measures. Precise staging of the cervical nodes is therefore of utmost importance, to ensure an accurate prognosis and provision of the most appropriate treatment. In patients with cT1-T2 oral/oropharyngeal squamous cell cancer, involvement of the cervical lymph nodes is associated with a 50% decrease in 5-year survival and represents the most important prognostic factor in this patient group.
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